Seabirds in crisis: Plastic ingestion induces proteomic signatures of multiorgan failure and neurodegeneration.

Understanding plastics' harmful impacts on wildlife would benefit from the application of hypothesis agnostic testing commonly used in medical research to detect declines in population health. Adopting a data-driven, proteomic approach, we assessed changes in 745 proteins in a free-living nonmodel organism with differing levels of plastic exposure. Seabird chicks heavily affected by plastic ingestion demonstrated a range of negative health consequences: Intracellular components that should not be found in the blood were frequently detected, indicative of cell lysis.

Validation of markerless video-based gait analysis using pose estimation in toddlers with and without neurodevelopmental disorders.

Introduction: The onset of locomotion is a critical motor milestone in early childhood and increases engagement with the environment. Toddlers with neurodevelopmental disabilities often have atypical motor development that impacts later outcomes. Video-based gait analysis using pose estimation offers an alternative to standardized motor assessments which are subjective and difficult to ascertain in some populations, yet very little work has been done to determine its accuracy in young children.

Lactobacillus acidophilus (strain Scav) Postbiotic Metabolites Reduce Infection and Modulate Inflammation in an in vivo model of Pseudomonas aeruginosa wound infection.

Aims: This study assessed the antibacterial, anti-biofilm, and immunomodulatory activity of Lactobacillus acidophilus (strain Scav) postbiotic (LaP) in a mouse model of Pseudomonas aeruginosa wound infection and evaluated the bioactive components of the LaP.

Methods And Results: LaP was tested for P. aeruginosa clearance and immunomodulatory activity during wound infection.

Sex-specific performances, trade-offs, and trait repeatability across the lifetime of the world's largest semelparous mammal (Dasyurus hallucatus).

The activities that define survival and reproductive success in animals depend on their physical performances. However, performance is a complex trait, and organisms must balance competing demands of multiple underlying factors every time they undertake an activity. For example, the morphology that increases bite force (i.