[Blood biochemical parameters of tilted primates periodically subjected to gravitational stimuli].

Head-down tilting of primates (HOT) is a universal method of studying the hypokinetic syndrome effects on functionality of various body systems. Clinical biochemical blood assay was performed in a 25-day HDT experiment (-5 degrees) with 11 Macaca rhesus. One group of animals was kept tilted all the time through, whereas the other was periodically returned into the orthostatic position for 30 to 120 minutes 4-5 times a week.

Metabolic parameters of Bion 11 monkeys.

Biochemical parameters of protein, carbohydrate, and fluid-electrolyte metabolism were measured in the blood of Bion 11 rhesus monkeys. The 14-day flight induced changes in total protein, BUN, and calcium, which were also seen in humans during long-duration space missions. It was concluded that protein and calcium metabolism changed while carbohydrate metabolism remained unaltered.

[Influence of polyethylene oxide Polyox WSR-301 on the pressure in mesenteric arterial microvessels in rats pre-adapted to anti-orthostatic states].

High-molecular polymers apt to directly influence flow microstructure were tested as a fundamentally new method for correcting microhemodynamics in microgravity. Pressure in the mesenteric arterial microvessels was measured two weeks in rats adapted to the head-down suspension. Intravenous polyethylene oxide (Polyox WSR-301, end-concentration in the order of 2.