Publications by authors named "R I Chalanova"

Clinical patterns of ocular burn in patients with different types and variants of stress reactivity were studied. It is shown that patients with the maladaptive type of stress reactivity at any stage of the disease are at higher risk of complications. Rapid exhaustion of the sympathoadrenal system or a hyperactive stress response seen in cases of the labile and hyperergic individual adrenergic immune reactivity of the organism (IAIRO) can be considered as manifestations of a regulation disorder.

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A series of clinical and immunological studies revealed peculiarities of stress reactivity in the course of ocular burn. According to adrenergic receptor expression level in active T-lymphocytes and its trend in the dynamics of ocular burn 2 types and 7 variants of individual adrenergic immune reactivity were identified and a physiologically adequate variant of stress reactivity was determined.

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The individual adrenergical immunological reactivity of the organism (IA IRO) was investigated in 142 patients with eye burn of various degree. 2 types of IA IRO have been allocated by level and orientation of T-adrenoreception dynamics changes.

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We used fluorescence angiography to study the vascular microcirculation in the anterior eye segment of 14 patients with severe eye bums. The severity of eye burns is not only related with an impaired blood circulation in the conjunctiva, it also depends on a microcirculation status of episcleral vessels. Different degrees of permeability of fluorescein through the conjunctival or episcleral vessels make it possible to specify circulation disorders in both cases.

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One hundred and two (128 eyes) patients with stage 4 ocular burns underwent examinations. One-stage therapeutic keratoplasty was used in 67 (67.7%) patients.

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