Publications by authors named "R I Cano"
(1) Background: , a lactic acid-producing bacterium, displays characteristics of both and genera. Clinical evidence suggests its potential health benefits. This study evaluated the safety of AO1167B as a candidate probiotic supplement.
View Article and Find Full Text PDFObjective: To develop and validate a patient-reported definition of acute calcium pyrophosphate (CPP) crystal arthritis in people with crystal-proven CPP deposition (CPPD) disease.
Methods: Consecutive patients with crystal-proven CPPD disease from seven centres across four countries were enrolled in a cross-sectional study. In each centre, patient-reported outcomes on the features of acute CPP crystal arthritis were collected.
Objective: This study aimed to analyze and compare the organization and care offered by Primary Health Care (PHC) to people with suspected and/or diagnosed COVID-19 in Brazilian municipalities, considering the Human Development Index (HDI).
Methods: This is an analytical cross-sectional study carried out with managers of PHC services in Brazilian municipalities. The data were collected using a self-administered questionnaire via Google Forms between April and September 2022 and were analyzed using prevalence ratios, using a Poisson regression model with a random effect and a 5% significance level.
Mutations in protein -glucosyltransferase 1 ( ) cause a recessive form of limb-girdle muscular dystrophy (LGMD-R21) associated with reduced satellite cell number and NOTCH1 signaling in adult patient muscles and impaired myogenic capacity of patient-derived muscle progenitors. However, the roles of POGLUT1 in the development, function, and maintenance of satellite cells are not well understood. Here, we show that conditional deletion of mouse in myogenic progenitors leads to early lethality, postnatal muscle growth defects, reduced expression, abnormality in muscle extracellular matrix, and impaired muscle repair.
View Article and Find Full Text PDFArticle Synopsis
- AO1125 is a Gram-positive bacterium with potential probiotic benefits due to its broad antimicrobial activity and resilience in gut conditions.
- The study assessed its safety and probiotic capabilities through genome analysis, cytotoxicity tests, and a clinical trial with 99 healthy participants.
- Results indicate minimal antibiotic resistance and no harmful effects, making AO1125 a promising candidate for supporting gut health and a potential focus for future research.