Publications by authors named "R Hodge"
Background: Diet plays a vital role in human health and environmental effects. Monitoring diet quality and its relationship to both health and environment are essential for policy making.
Objectives: This study aimed to analyze trends in the Planetary Health Diet Index (PHDI) and its associations with daily greenhouse gas emissions from food (GHG), disease-related biomarkers, anthropometric measurements, obesity, and all-cause mortality in the US population.
Background: The Overall Plant-based Diet Index (PDI), the Healthful Plant-based Diet Index (hPDI), and the Unhealthful Plant-based Diet Index (uPDI) are relatively new tools for characterizing the quality of plant-based dietary patterns in epidemiologic studies. Reproducibility and validity of these indices have not been assessed across populations.
Objective: The objective of this study was to evaluate the reproducibility and validity of PDI, hPDI, and uPDI in a racially and ethnically diverse population.
Article Synopsis
- - The study aimed to explore the relationship between non-nutritive sweetener (NNS) consumption and diet quality, using data from the American Cancer Society's cancer prevention study with over 163,000 participants.
- - Results showed that consumers of NNS generally had lower diet quality compared to non-consumers, as indicated by decreases in both the ACS diet score and the Healthy Eating Index scores with increased NNS intake.
- - Additionally, the likelihood of having a low diet quality increased with higher NNS consumption, indicating that those who consumed 2 or more servings of NNS daily had significantly higher odds of poor diet quality.
In this review, we introduce the concept of cell competition, which occurs between heterogeneous neighboring cell populations. Cells with higher relative fitness become "winners" that outcompete cells of lower relative fitness ("losers"). We discuss the idea of super-competitors, mutant cells that expand at the expense of wild-type cells.
View Article and Find Full Text PDFAlzheimer's disease (AD) is the leading cause of dementia in older adults. Although AD progression is characterized by stereotyped accumulation of proteinopathies, the affected cellular populations remain understudied. Here we use multiomics, spatial genomics and reference atlases from the BRAIN Initiative to study middle temporal gyrus cell types in 84 donors with varying AD pathologies.
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