Publications by authors named "R Hiratsuka"
Background And Aims: Fertilization relies on pollen mother cells able to transition from mitosis to meiosis to supply gametes. This process involves remarkable changes at the molecular, cellular and physiological levels, including (but not limited to) remodelling of the cell wall. During the onset of meiosis, the cellulose content in the pollen mother cell walls gradually declines, with the concurrent deposition of the polysaccharide callose in anther locules.
View Article and Find Full Text PDFPurpose: To validate the international chronic ocular graft-versus-host disease (GVHD) diagnostic criteria (ICCGVHD) compared to the National Institute of Health diagnostic criteria 2014 (NIH2014) for chronic ocular GVHD.
Methods: Between 2013 and 2019, the study enrolled 233 patients with or without chronic ocular GVHD combined with the presence or absence of systemic chronic GVHD in an internationally prospective multicenter and observational cohort from 9 institutions. All patients were evaluated for four clinical parameters of ICCGVHD.
Context: Family functioning is a modifiable factor associated with major depressive disorder (MDD) and complicated grief (CG) among the bereaved families of patients with advanced cancer; however, the evidence regarding this association is limited.
Objectives: We aimed to explore the association of family functioning with possible MDD and CG among the bereaved families of patients with advanced cancer who died in palliative care units.
Methods: This study is a part of the J-HOPE4 study, a nationwide cross-sectional multi-purpose questionnaire survey conducted in 2018.
Article Synopsis
- - The study investigates the role of 1,3-β-D-glucan (BG) in Japanese cedar pollen (JCP) and its potential effects on immune responses, particularly in the context of type-I hypersensitivity associated with Japanese cedar pollinosis.
- - Researchers used immunohistochemical techniques to locate BG within JCP grains and examined its ability to stimulate dendritic cells, finding that BG enhances the production of specific cytokines and antibodies in mice exposed to JCP.
- - The results indicate that BG acts as an immune adjuvant, facilitating the production of JCP-specific IgE and IgG antibodies through a mechanism involving the dectin-1 receptor.