The Crosstalk Between Cartilage and Bone in Skeletal Growth.

While the flat bones of the face, most of the cranial bones, and the clavicles are formed directly from sheets of undifferentiated mesenchymal cells, most bones in the human body are first formed as cartilage templates. Cartilage is subsequently replaced by bone via a very tightly regulated process termed endochondral ossification, which is led by chondrocytes of the growth plate (GP). This process requires continuous communication between chondrocytes and invading cell populations, including osteoblasts, osteoclasts, and vascular cells.

Enhanced extraction of methylene blue by dodecyl-methyl imidazolium dodecyl sulfate GUMBOS - magnetic alginate beads.

In this study, dodecyl-methyl imidazolium dodecyl sulfonate ([CMIm][DS]) GUMBOS were synthesized and incorporated into alginate with γ-FeO to fabricate magnetic adsorbent beads ([C₁₂MIm][DS]-beads) for methylene blue (MB) removal. Characterization via ESI-MS, FT-IR, SEM, BET, and TGA confirmed their structure and properties. The beads achieved a maximum adsorption capacity of 4.

A patient reported outcome measure for rectal cancer patients eligible for organ preservation: Development and validation of a Watch-and-Wait module for the Assessment of Burden of disease in ColoRectal Cancer (ABCRC) tool.

Aim: The Assessment of Burden of ColoRectal Cancer (ABCRC)-tool is an integrated tool, developed in conjunction with colorectal cancer (CRC) patients, that measures the experienced burden of disease and lifestyle parameters and visualizes the results. To provide tailored follow-up care for watch-and-wait (WW) patients, in line with their specific needs and preferences, a WW module for the ABCRC-tool was developed. In this paper we describe the development and validation process of the WW module.

Disentangling the relationship between biological age and frailty in community-dwelling older Mexican adults.

Background: Older adults have highly heterogeneous aging rates.

Objective: To explore the association of biological age (BA) and accelerated aging with frailty in community-dwelling older adults.

Methods: We assessed 735 community-dwelling older adults from the Coyocan Cohort.

Ultrasound evaluation of superficial lesions caused by ectoparasites in children.

Ectoparasites affect the skin, causing different clinical manifestations through direct mechanical damage, blood consumption, pathogen transmission, hypersensitivity reactions, or toxin inoculation. Dermatological ultrasound is the imaging modality of choice to evaluate these superficial lesions, detecting submillimetric alterations in a non-invasive and innocuous way. This review helps the radiologist describe the imaging findings of lesions caused by mosquitoes, myiasis, bees, spiders, and scorpions, with suggestive ultrasound patterns.