Publications by authors named "R Heermann"
The impact of chlorination on quorum sensing molecules (QSMs) is not often addressed in disinfection research. Yet pathogenicity and biofilm formation are controlled by quorum sensing (QS) in many bacteria. Chemical transformation of the compounds could have an impact on all of these processes.
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- Bioluminescence serves key roles in various organisms, but the function of light production in certain terrestrial bacteria is not well understood.
- The bacteria in question exist in two forms: primary cells that produce bright light and secondary cells that give off a dim light while colonizing different organisms.
- Research shows that while bioluminescence is important for the primary cells' interactions with insects and nematodes, it is not necessary for the bacteria's survival, making these modified cells useful for scientific assays.
Mycosis fungoides (MF) is the most common entity of Cutaneous T cell lymphomas (CTCL) and is characterized by the presence of clonal malignant T cells in the skin. The role of the skin microbiome for MF development and progression are currently poorly understood. Using shotgun metagenomic profiling, real-time qPCR, and T cell receptor sequencing, we compared lesional and nonlesional skin of 20 MF patients with early and advanced MF.
View Article and Find Full Text PDFUnlabelled: tarch tilization ystem (Sus)D-homologs are well known for their carbohydrate-binding capabilities and are part of the operon in microorganisms affiliated with the phylum Bacteroidota. Until now, SusD-like proteins have been characterized regarding their affinity toward natural polymers. In this study, three metagenomic SusD homologs (designated SusD1, SusD38489, and SusD70111) were identified and tested with respect to binding to natural and non-natural polymers.
View Article and Find Full Text PDFInvasive dental procedures, such as wisdom teeth removal, have been identified as potential triggers for vascular events due to the entry of oral bacteria into the bloodstream, leading to acute vascular inflammation and endothelial dysfunction. This study presents the case of a 27-year-old healthy male who developed ischemic stroke resulting from bacteremia after undergoing wisdom teeth extraction. Initially, the patient experienced fever and malaise, which were followed by right-sided hemiplegia.
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