Publications by authors named "R Hauer"

Arrhythmogenic cardiomyopathy (ACM) is a genetically heterogeneous inherited cardiomyopathy with an estimated prevalence of 1:5000-10 000 that predisposes patients to life-threatening ventricular arrhythmias (VA) and sudden cardiac death (SCD). ACM diagnostic criteria and risk prediction models, particularly for arrhythmogenic right ventricular cardiomyopathy (ARVC), the most common form of ACM, are typically genotype-agnostic, but numerous studies have established clinically meaningful genotype-phenotype associations. Early signs of ACM onset differ by genotype indicating the need for genotype-specific diagnostic criteria and family screening paradigms.

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We theoretically investigate the tomographic reconstruction of the three-dimensional photonic environment of nanoparticles. As input for our reconstruction we use electron energy loss spectroscopy (EELS) maps for different rotation angles. We perform the tomographic reconstruction of surface polariton fields for smooth and rough nanorods and compare the reconstructed and simulated photonic local density of states, which are shown to be in very good agreement.

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Article Synopsis
  • The study investigates patients with right bundle branch block (RBBB)-ventricular tachycardia (VT) and arrhythmogenic cardiomyopathy (ACM) by examining ECG characteristics of sinus rhythm (SR) and VT.
  • It included 70 patients, revealing that the most common sites of origin for the VTs were primarily in the inferior and lateral walls of the left ventricle (LV), with a good correlation to electro-anatomic mapping (EAM) data.
  • The findings highlight frequent abnormalities in SR depolarization and repolarization, which are associated with clinical implications in patients with ACM and RBBB-VT.
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