Publications by authors named "R Hata"
Various N-terminal tags have often been used to identify the functions and localization of Rab small GTPases, but their impact on Rab proteins themselves has been poorly investigated. Here, we used a knockout (KO)-rescue approach to systematically evaluate the effect of N-terminal tagging of two Rabs, Rab10 and Rab27A, on Rab10-KO HeLa cells and Rab27A-deficient melanocytes (melan-ash cells), respectively. The results showed that all of the N-terminal-tagged Rab27A proteins mediated actin-based melanosome transport in the melan-ash cells, but none of the N-terminal-tagged Rab10 proteins fully rescued the defect in tubular endosome formation in the Rab10-KO cells.
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- The study investigates whether ChatGPT can effectively triage simulated disaster patients using the START protocol by examining its repeatability, reproducibility, and accuracy.* -
- A total of 35,190 simulated triage cases were evaluated using prompts from disaster medicine physicians and compared against expert-assigned triage codes.* -
- Results showed that while ChatGPT successfully generated valid triage scores in 99.7% of cases, its accuracy was only 63.9%, with notable issues in overtriage (32.9%) and undertriage (3.1%).*
The transition of the sexual mode occurs widely in animal evolution. In nematodes, androdioecy, a sexual polymorphism composed of males and hermaphrodites having the ability to self-fertilize, has evolved independently multiple times. While the modification of noncoding regulatory elements likely contributed to the evolution of hermaphroditism, little is known about these changes.
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- A study examined the clinical outcomes of patients with blunt splenic injuries who received transarterial embolization (TAE), focusing on their hemodynamic status (stable vs unstable).
- The research analyzed data from 38 adult patients treated at two centers from 2011 to 2022, comparing the survival rates, rebleeding incidents, and need for splenectomy between hemodynamically stable (HDS) and unstable (HDU) groups.
- Results showed a high survival discharge rate for both groups (88.2% in HDU and 100% in HDS), but highlighted the need for more studies to assess the effectiveness of TAE compared to traditional surgery for HDU patients.
Introduction: This study is a scoping review to identify literature pertinent to the question: "What are the criteria for deployment of the United States National Guard (USNG) to domestic sudden-onset natural disasters (SODs)?" As this question relies on factors across many disciplines-legal, medical, technical, cultural-and as there is no foundational body of academic literature or unified governmental or USNG policy addressing this question, a scoping review was designed to identify the body of literature on which further research and policy decisions surrounding this question may be based.
Materials And Methods: On January 23, 2023 a modified PRISMA-ScR search was performed using an online search engine of the following databases: Academic Search Premier, Google Scholar, JSTOR, PubMed, Web of Science, and WorldCat. The inclusion criteria included the involvement of the USNG response to U.