Publications by authors named "R Happle"
Pioneers in Dermatology and Venereology: An interview with Professor Rudolf Happle.
J Eur Acad Dermatol Venereol
May 2024
Incontinentia pigmenti (IP) is a rare X-linked dominant, male-lethal disorder characterized by pathognomic skin lesions. As described in the literature the typical cutaneous changes follow the pattern of Blaschko's lines and develop in four stages that usually start at birth. Stage 1 is called vesicular, bullous or inflammatory.
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- There is ongoing confusion about whether hereditary perifollicular fibromas and fibrofolliculomas are distinct skin tumors.
- Histopathological evidence shows that these tumors are actually the same, despite historical claims that fibrofolliculomas were an unrecognized type of tumor.
- It is important to differentiate between hereditary nonsyndromic perifollicular fibromas and the syndromic types associated with conditions like colon cancer, as understood through past research by various groups.