Congenital esophageal stenosis in adults.

Objective: Congenital esophageal stenosis is thought to be a rare disease confined to infancy and childhood with only a few case reports in adults described.

Methods: We report five patients between the ages of 19 and 46 yr who presented with this disorder over a 2-yr period.

Results: Patients had been labeled with reflux strictures, webs, or as idiopathic in the past.

Bedtime ranitidine does not eliminate the need for a second daily dose of omeprazole to suppress nocturnal gastric pH.

Background: We have previously shown that 70% of patients experience nocturnal gastric acid breakthrough (defined as pH<4 for more than 60 min between 22.00 and 06.00 hours) on twice a day (b.