Publications by authors named "R Hamkar"
Objective: Human papillomavirus (HPV) vaccination is currently not included in the national vaccination program in Iran. Regional data on the distribution of HPV types in women are important as they can predict the impact of currently available vaccines and help health policy makers to consider all the possibilities with regard to HPV vaccination.
Methods: A total of 1,218 Iranian women with normal cervical cytology were included in this study.
Article Synopsis
- - The research indicates that different variants of HPV 16, particularly lineages A and D, vary in their potential to cause cancer and their geographic distribution, emphasizing the importance of studying these regional variants.
- - In a study of 106 HPV 16 isolates, lineage D was found to be predominant, making up 70.7% of the samples, while lineage A comprised 29.3%, with lineage D also dominant in both normal and precancerous cervical conditions.
- - Although lineage A appeared more frequently in cervical cancer cases (20% in normal+CIN I-II vs. 33.8% in CIN III+ICC), the difference was not statistically significant, reinforcing the higher prevalence of lineage D in Iran
In Iran, human papillomavirus (HPV) vaccination is not currently included in the national vaccination program and there are no comprehensive approaches to cervical screening program. Regional data on distribution of HPV types in women is important to predict the impact of current HPV vaccines. Although several studies on distribution of HPV types in cervical precancer and cancer have been conducted in Iran, in most of them HPV positive samples were subjected to specific-primer genotyping (mainly 16 and 18), and leaving the other HPV genotypes almost undetermined.
View Article and Find Full Text PDFBackground: Inverted papilloma (IP) is an uncommon disease which arises in the mucosal membrane of the nasal cavity and paranasal sinus. It has been proposed that human papillomavirus (HPV) is the causal agent in the pathogenesis of IP and plays a key role in the progression from benign IP to malignancy. As there are no prior studies that focus on an Iranian population, this study intended to characterize the prevalence of HPV types in benign and malignant forms of IP.
View Article and Find Full Text PDFArticle Synopsis
- BK virus (BKV) is a common virus that affects a majority of the population but mainly causes issues in patients with weakened immune systems, such as those on dialysis.
- A study involving 63 hemodialysis (HD) and 33 peritoneal dialysis (PD) patients in Tehran aimed to assess the prevalence of BKV in these groups.
- Results showed a low prevalence of BK viremia at 3.03% for PD patients and 0% for HD patients, indicating unique patterns of BKV infection among Iranian dialysis patients compared to other populations.