Publications by authors named "R Hama"
Article Synopsis
- Dorset sheep are often used in cardiovascular research due to their similarities to human anatomy and physiology, particularly for studying single-ventricle physiology.
- Researchers observed unexpected changes in central venous pressure that couldn’t be explained by gravity, leading them to investigate the inferior vena cava (IVC) for potential narrowing or compression.
- The study found significant differences in IVC dimensions and pressures based on body position, revealing more smooth muscle in the abdominal portion of the IVC compared to the thoracic part, which enhances understanding of sheep physiology and informs future research methods.
Effectiveness of methylene blue as a local anesthetic and analgesic in perianal operations: A prospective double-blind randomized control trial.
Curr Probl Surg
August 2024
Synaptic zinc ions (Zn) play an important role in the development of vascular dementia (VD) and Parkinson's disease (PD). In this article, we reviewed the current comprehension of the Zn-induced neurotoxicity that leads to the pathogenesis of these neuronal diseases. Zn-induced neurotoxicity was investigated by using immortalised hypothalamic neurons (GT1-7 cells).
View Article and Find Full Text PDFMacrophages are the primary cell type orchestrating bioresorbable vascular graft (BVG) remodeling and infiltrate from three sources: the adjacent native vessel, circulating blood, and transmural migration from outer surface of the graft. To elucidate the kinetics of macrophage infiltration into the BVG, we fabricated two different bilayer arterial BVGs consisting of a macroporous sponge layer and a microporous electrospun (ES) layer. The Outer ES graft was designed to reduce transmural cell infiltration from the outer surface and the Inner ES graft was designed to reduce cell infiltration from the circulation.
View Article and Find Full Text PDFWe have developed a functionalized silk fibroin (BSF) that can serve as an improved fundamental material for dressings by specifically capturing growth factors secreted during the healing process and supplying them to cells accumulated in the wound area to enhance the tissue regeneration efficiency. When considering the design of heparin-modified BSF, there is a difficulty with binding to high-molecular-weight polysaccharides without disrupting the hydrophobic crystalline structure of the BSF. In this study, a low-molecular-weight pharmaceutical heparin, dalteparin, was selected and cross-linked with the tyrosine residue presence in the BSF non-crystalline region.
View Article and Find Full Text PDF