Publications by authors named "R H Sia"
Article Synopsis
- This study evaluated the effects of LASIK, PRK, and SMILE surgeries on patient-reported outcomes among active-duty U.S. Military Servicemembers, focusing on vision quality and satisfaction before and after surgery.
- A total of 375 Servicemembers underwent these procedures, with results showing that 94-95% achieved 20/20 vision or better, with significant improvements in far vision for LASIK and PRK specifically.
- Overall, all three surgical options provided excellent visual outcomes and minimal side effects, enhancing daily activities for the Servicemembers six months post-operation.
Article Synopsis
- This study aimed to compare the early visual quality, specifically low contrast acuity (LCVA), between two types of eye surgery: SMILE and LASIK.
- The analysis involved military personnel who underwent either SMILE or two types of LASIK (wavefront-guided and wavefront-optimized), evaluating their night vision and LCVA up to three months after surgery.
- Results showed that LASIK patients had better night vision and photopic LCVA at one month compared to SMILE patients, while WFO LASIK had mixed results at three months, indicating that LASIK might lead to faster recovery of visual quality than SMILE.
Background: COVID-19 can induce a systemic inflammatory response with variable clinical manifestations. Similar to various viruses, COVID-19 has been implicated in the pathogenesis of autoimmune diseases. This article highlights the potential for infections including the SARS-CoV-2 virus to induce exacerbations of pre-existing autoimmune diseases or even potentially unmask de novo autoimmune diseases in particular anti-synthetase syndrome (ASSD) in predisposed individuals.
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- - TTA-UC (Triplet-triplet annihilation upconversion) in nanoparticle assemblies shows promise for biomedical applications, especially in drug delivery and imaging, needing good mobility of sensitizer and annihilator for effective energy collisions.
- - Liposomes offer advantages like fluidity and biocompatibility, but there are limited studies on their use in TTA-UC systems, which this research aims to address by introducing a BODIPY-based sensitizer within liposomes.
- - The study includes time-resolved spectroscopy and molecular dynamics simulations, revealing that triplet energy transfer between the sensitizer and annihilator is more effective in liposomes, enhancing the potential of these systems in TTA-UC applications.
BODIPY heterochromophores, asymmetrically substituted with perylene and/or iodine at the 2 and 6 positions were prepared and investigated as sensitizers for triplet-triplet annihilation up conversion (TTA-UC). Single-crystal X-ray crystallographic analyses show that the torsion angle between BODIPY and perylene units lie between 73.54 and 74.
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