Publications by authors named "R H Regev"
Background: X-linked hypophosphatemic rickets (XLH) is associated with uninhibited FGF23 activity, which leads to phosphaturia, hypophosphatemia and depressed active vitamin D (1,25OH2D) levels. Conventional treatment with phosphate supplements and vitamin D analogs may lead to hypercalciuria (HC), nephrocalcinosis (NC) and hyperparathyroidism. We investigated the effects of burosumab treatment, an anti-FGF23 monoclonal antibody recently approved for XLH, on these complications.
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- A study looked at how personality and thinking patterns relate to different obsessive-compulsive disorders (OCD) and similar issues.
- Researchers compared 239 patients with OCD and related disorders to 100 healthy individuals.
- They found that patients had higher levels of anxiety and lower levels of being outgoing and organized, with some unique differences between the types of disorders.
Article Synopsis
- The study investigated how treatment affects neurocognitive performance in individuals with OCD, focusing on symptom changes and the role of the BDNF Val66Met polymorphism as a genetic factor.
- Participants (N = 125) received various treatments, including cognitive behavioral therapy (CBT) and physical exercise, with assessments done before and after treatment to measure OCD symptoms and neurocognitive abilities.
- Results showed that while OCD symptoms improved with treatment, neurocognitive performance also enhanced independently of the BDNF genotype, indicating a strong link between symptom relief and cognitive function improvement.
Background: Exclusive breastfeeding (EBF) is recommended for the first 6 months of life, yet EBF rates at 6 months (T3) in most developed countries are low. Painful and nonpainful sensory stimuli processing is linked, and while pain has been suggested to restrict breastfeeding, its coupling with sensory over-responsiveness (SOR) in relation to breastfeeding has not yet been reported.
Objective: We aimed to explore whether breastfeeding-related pain, SOR, and general pain sensitivity predict nonexclusive breastfeeding (NEBF) at T3.
Background: Metabolic bone disease is a common manifestation of celiac disease (CD). We aimed to assess fracture risk among children and adolescents with CD compared with a matched group.
Methods: This registry-based cohort study included 2372 children with CD who were matched 1:5 to 11,860 children without CD.