Topical application of the ethanol extract and the hydroethanolic fraction of ripe Solanum lycocarpum A. St. Hil. fruit improves the healing of excisional wounds.

Purpose: To evaluate the effect of the topical application of the ethanol extract (EESL) and the hydroethanolic fraction (HFSL) of ripe Solanum lycocarpum fruit on the healing of experimentally-induced wounds in mice.

Methods: The EESL and HFSL obtained from ripe fruit of the species S. lycocarpum were obtained by percolation with ethanol.

Earth-abundant transition metal complexes in light-emitting electrochemical cells: successes, challenges and perspectives.

Light-emitting electrochemical cells (LECs) are an attractive technology in the field of solid state light devices (SSLDs) as their simple architectures allow the preparation of cost-effective lighting devices. Consequently, low-cost and sustainable emitters are highly desirable. Transition metal complexes are attractive in this field as they have been proved to possess compatible optoelectronic properties.

Exploring the therapeutic potential of acorn extract in papillomavirus-induced lesions.

Background And Aim: Papillomaviruses (PVs) infections have been documented in numerous animal species across different regions worldwide. They often exert significant impacts on animal health and livestock production. Scientists have studied natural products for over half a century due to their diverse chemical composition, acknowledging their value in fighting cancer.

Prenatal couple relationship satisfaction, romantic attachment, and childbirth-related posttraumatic stress symptoms.

Background: Traumatic childbirth can lead to childbirth-related posttraumatic stress symptoms (CB-PTSS). Although underexplored, prenatal couple relationship satisfaction and romantic attachment orientations are modifiable factors that may increase or mitigate the risk of CB-PTSS after a traumatic childbirth experience.

Objectives: This study examined (1) the associations between prenatal couple relationship satisfaction and romantic attachment, traumatic childbirth and CB-PTSS; (2) whether prenatal couple relationship satisfaction moderates the association between traumatic childbirth and CB-PTSS; and (3) whether the interaction between prenatal couple relationship satisfaction and romantic attachment moderates the association between traumatic childbirth and CB-PTSS.

A comparative study of two data-driven modeling approaches to predict drug release from ER matrix tablets.

The pharmaceutical industry is striving to develop innovative and promising tools, increasingly embracing new data-driven approaches, to understand, improve and accelerate the drug product development process. While extended release (ER) oral formulations offer a number of advantages, including maintenance of therapeutic drug levels, a reduction in dosing frequency, and minimization of side effects, achieving consistent drug release profiles remains a significant challenge. As a critical attribute for drug absorption into systemic circulation, in vitro dissolution testing represents a time-consuming and complex method for the evaluation of such formulations.