Wavefront-aberration-tolerant diffractive deep neural networks using volume holographic optical elements.

As the demand for computational performance in artificial intelligence (AI) continues to increase, diffractive deep neural networks (DNNs), which can perform AI computing at the speed of light by repeated optical modulation with diffractive optical elements (DOEs), are attracting attention. DOEs are varied in terms of fabrication methods and materials, and among them, volume holographic optical elements (vHOEs) have unique features such as high selectivity and multiplex recordability for wavelength and angle. However, when those are used for DNNs, they suffer from unknown wavefront aberrations compounded by multiple fabrication errors.

Response Shifts in the Canadian Occupational Performance Measure: A Convergent Mixed-Methods Study.

Importance: A response shift (RS) is a phenomenon in which there is an individual perceptual gap between pre and post assessments. RS effects were not considered in the Canadian Occupational Performance Measure (COPM) development process.

Objective: To detect the effects of RS on the COPM.

Nationwide status of progestogen treatment to prevent spontaneous preterm birth: A questionnaire survey for childbirth healthcare facilities in Japan.

Aim: This study aimed to investigate the current status of progestogen treatment for pregnant women at a high risk for preterm birth (PTB) in childbirth healthcare facilities in Japan.

Methods: A web-based nationwide questionnaire survey regarding progestogen use for prevention of PTB was conducted among childbirth healthcare facilities from 2019 to 2021.

Results: Valid responses were obtained from 528 facilities (25.

S2P intramembrane protease RseP degrades small membrane proteins and suppresses the cytotoxicity of intrinsic toxin HokB.

The site2protease (S2P) family of intramembrane proteases (IMPs) is conserved in all kingdoms of life and cleaves transmembrane proteins within the membrane to regulate and maintain various cellular activities. RseP, an S2P peptidase, is involved in the regulation of gene expression through the regulated cleavage of the two target membrane proteins (RseA and FecR) and in membrane quality control through the proteolytic elimination of remnant signal peptides. RseP is expected to have additional substrates and to be involved in other cellular processes.

Hybrid in vitro/in silico analysis of low-affinity protein-protein interactions that regulate signal transduction by Sema6D.

Semaphorins constitute a large family of secreted and membrane-bound proteins that signal through cell-surface receptors, plexins. Semaphorins generally use low-affinity protein-protein interactions to bind with their specific plexin(s) and regulate distinct cellular processes such as neurogenesis, immune response, and organogenesis. Sema6D is a membrane-bound semaphorin that interacts with class A plexins.