Publications by authors named "R H Keogh"
Background: Children with cystic fibrosis (CF) from socioeconomically deprived areas have poorer growth, worse lung function, and shorter life expectancy than their less-deprived peers. While early growth is associated with lung function around age 6, it is unclear whether improving early growth in the most deprived children reduces inequalities in lung function.
Methods: We used data from the UK CF Registry, tracking children born 2000-2010 up to 2016.
Majorana quasiparticles and topological phases in 3D active nematics.
Proc Natl Acad Sci U S A
December 2024
Quasiparticles are low-energy excitations with important roles in condensed matter physics. An intriguing example is provided by Majorana quasiparticles, which are equivalent to their antiparticles. Despite being implicated in neutrino oscillations and topological superconductivity, their experimental realizations remain very rare.
View Article and Find Full Text PDFBackground: Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a supportive therapy for acute respiratory failure with increased risk of packed red blood cells (PRBC) transfusion. Blood cell salvage (BCS) aims to reduce blood transfusion, but its efficacy is unclear. This study aimed to estimate the effect of BCS at the time of removal of the ECMO circuit (ECMO decannulation) on PRBC transfused.
View Article and Find Full Text PDFArticle Synopsis
- Prediction models help make medical decisions by estimating risks, advising high-risk individuals to undergo interventions while suggesting low-risk individuals avoid them.
- Traditional models may overlook the complexities of interventions since they often assess risk at just one point in time, while in reality, decisions are made repeatedly and may change over time.
- The article discusses how to formulate estimands for making better sequential predictions about interventions, using the example of choosing between vaginal delivery and cesarean section to inform future research and improve decision-making in clinical practice.
Introduction: Although treatment advances have improved survival rates for patients with metastatic breast cancer (MBC), patient expressed needs have not been evaluated in Ireland to date.
Methods: A 76 item questionnaire was designed by the lead author and a cohort of 41 other MBC patients in collaboration with a multidisciplinary team. The online survey was publicised nationally on all media platforms.