Publications by authors named "R H Hagemann-Madsen"
Article Synopsis
- The study evaluated colorectal cancer (CRC) and advanced adenoma risks in participants with adenomas in a Danish FIT-based screening program, challenging previous adenoma surveillance guidelines.
- In the analysis of nearly 10,000 follow-up examinations, the high-risk group experienced lower CRC occurrence compared to the intermediate risk group, while advanced adenoma risk was higher among those deemed high risk.
- Findings suggest that initial screening results may not accurately predict CRC risk in populations that test positive in FIT screenings, indicating a need for potential guideline revisions.
Introduction: Magnetic resonance enterography (MRE) is useful for detecting bowel strictures, whereas a number of imaging biomarkers may reflect severity of fibrosis burden in Crohn's disease (CD). This study aimed to verify the association of MRE metrics with histologic fibrosis independent of inflammation.
Methods: This prospective European multicenter study performed MRE imaging on 60 patients with CD with bowel strictures before surgical resection.
Collagenous sprue is a rare enteropathy affecting the small intestinal mucosa and can resemble and coincide with coeliac disease or collagenous colitis. To our knowledge, less than 175 cases of collagenous sprue have been described. Both clinicians and pathologists should be aware of the condition in order to adequately target their investigations and treatment.
View Article and Find Full Text PDFThe disparity in outcomes for low rectal cancer may reflect differences in operative approach and quality. The extralevator abdominoperineal excision (ELAPE) was developed to reduce margin involvement in low rectal cancers by widening the excision of the conventional abdominoperineal excision (c-APE) to include the posterior pelvic diaphragm. This study aimed to determine the prevalence and localization of inadvertent residual pelvic diaphragm on postoperative MRI after intended ELAPE and c-APE.
View Article and Find Full Text PDFIntroduction: Treatment options for peritoneal metastases (PM) from colorectal cancer (CRC) have increased, their efficiency should be monitored. For this purpose, register-based data on PM can be used, if valid.
Purpose: We aimed to evaluate the completeness and positive predictive value (PPV) of synchronous peritoneal metastases (S-PM) registered among CRC patients in the Danish National Patient Register (DNPR) and/or the Danish National Pathology Register (the DNPatR) using the Danish Colorectal Cancer Group database (DCCG) as a reference.