Publications by authors named "R H Fagan"
Background: Commissioning for health services has been implemented as one approach to improve the quality and access to healthcare for First Nations, regional and remote populations. This review systematically scoped the literature for studies that described or evaluated the governance, funding, implementation and outcomes from health service commissioning targeting these groups in Canada, Australia, Aotearoa/New Zealand and the United States (CANZUS nations).
Methods: Seventeen databases were searched for relevant peer reviewed and grey literature studies published in English from 2010 to 2023.
Background: Breast cancer survivors (BCS) may experience cardiotoxicities from chemotherapy and oral endocrine therapy. Although a few studies have documented that palpitations are prevalent and associated with poorer outcomes, there is limited to no information on BCS' reporting of palpitations to healthcare providers.
Objectives: To compare BCS who did and did not report their palpitations to a healthcare provider and describe how those who did report palpitations recalled their provider responding.
Perfusion Bioreactor Conditioning of Small-diameter Plant-based Vascular Grafts.
Tissue Eng Regen Med
December 2024
Article Synopsis
- Vascular grafts typically made from synthetic materials face issues like thrombosis and intimal hyperplasia, especially in small diameters, prompting research into alternative options such as decellularized plant scaffolds.* -
- The study developed a novel bioreactor to precondition small-diameter vascular grafts made from decellularized leatherleaf viburnum, simulating physiological conditions to enhance cell density and reduce thrombus formation.* -
- Results showed that bioreactor conditioning improved the grafts’ endothelial cell density and suture retention while maintaining cell viability, indicating the potential of these plant-based grafts for vascular repair with lower risk of blood clots.*
Article Synopsis
- Clostridioides difficile is a bacteria that can cause serious infections, and there aren’t many medicines to treat it, mainly vancomycin.
- Recently, some bacteria have started to resist vancomycin, but C. difficile hasn’t shown high-level resistance yet.
- Scientists found that C. difficile can quickly develop resistance, but this makes it less able to spread and survive, which might help doctors keep it under control.
Objectives: To further develop an understanding of laypeople's (adult patients and public) beliefs and attitudes toward antimicrobial resistance (AMR) by developing a conceptual model derived from identifying and synthesizing primary qualitative research.
Methods: A systematic search of 12 electronic databases, including CINAHL, MEDLINE, PsycINFO, PubMed and Web of Science to identify qualitative primary studies exploring patient and public understanding of AMR published between 2012 and 2022. Included studies were quality appraised and synthesized using Noblit and Hare's meta-ethnographic approach and reported using eMERGe guidance.