Publications by authors named "R H Augsburger"
Objective: Limb-girdle muscular dystrophy R9 (LGMDR9, formerly known as LGMD2I), caused by variants in the fukutin-related protein (FKRP) gene leads to progressive muscle weakness of the shoulder and pelvic limb-girdles and loss of motor function over time. Clinical management and future trial design are improved by determining which standardized clinical outcome assessments (COA) of function are most appropriate to capture disease presentation and progression, informing endpoint selection and enrollment criteria. The purpose of our study was to evaluate the cross-sectional validity and reliability of clinical outcome assessments in patients with FKRP-related LGMDR9 participating in the Genetic Resolution and Assessments Solving Phenotypes in LGMD (GRASP) natural history study.
View Article and Find Full Text PDFObjectives: The formation of new bone by periosteum due to an insult is called periosteal bone reaction (PBR). This study assessed the cone beam computed tomography (CBCT) patterns of periosteal bone reactions associated with periapical inflammatory lesion (apical periodontitis/periapical rarefying osteitis).
Materials And Methods: Twenty-two small field of view CBCT images of patients with PBR were selected from a database of a private practice limited to endodontics.
Study Design: Randomized, controlled single-blind cross over study. This study was registered on ClinicalTrials.gov (NCT02473614).
View Article and Find Full Text PDFIntroduction: Artifacts created by the presence of metal objects in the jaw negatively affect the cone-beam computed tomographic image quality. This study compares artifacts produced by metal objects outside of the field of view (FOV) in a small FOV CBCT image with those produced in a large FOV image in which the metal object is within the FOV.
Methods: We methodically placed 4 titanium implant-sized rods and 4 zirconium crown-sized disks on 1 side of a human cadaver mandible.
Article Synopsis
- High doses of home-based telerehabilitation (TR) show promise for stroke recovery, addressing common barriers like access and compliance through supervised therapy that incorporates games, sensor technology, and daily assessments.
- The study involved 13 stroke patients who engaged in tailored TR for 12 weeks, demonstrating feasibility with over 79% initiation and 65% completion of therapy sessions, although compliance decreased in the later weeks.
- Results indicated improvements in motor function scores, especially for arm movements, and successful monitoring of patient fatigue and other outcomes, emphasizing the potential of a holistic TR approach in rehabilitation.