Peptriever: a Bi-Encoder approach for large-scale protein-peptide binding search.

Motivation: Peptide therapeutics hinge on the precise interaction between a tailored peptide and its designated receptor while mitigating interactions with alternate receptors is equally indispensable. Existing methods primarily estimate the binding score between protein and peptide pairs. However, for a specific peptide without a corresponding protein, it is challenging to identify the proteins it could bind due to the sheer number of potential candidates.

Public Health Data in Action: An Analysis of Using Louisiana Vital Statistics for Quality Improvement and Payment Reform.

Introduction In 2012, the Louisiana (LA) Department of Health and Hospitals revised the LA birth certificate to include medical reasons for births before 39 completed weeks' gestation. We compared the completeness and validity of these data with hospital discharge records. Methods For births occurring 4/1/2012-9/30/2012 at Woman's Hospital of Baton Rouge, we linked maternal delivery and newborn birth data collected through the National Perinatal Information Center with LA birth certificates.

The risk of breast cancer in relation to health habits and occupational exposures.

Background: The age-adjusted incidence rate of breast cancer has increased for Israeli women. Our aim was to explore the hypothesis that occupational exposures are important risk factors, taking into consideration main known risk factors.

Methods: The study population included 326 breast cancer cases from one hospital in the center of the country and 413 women without known diagnosis of cancer.

Cancer incidence among laboratory workers in biomedical research and routine laboratories in Israel: Part II-nested case-control study.

Background: A case-control study nested within a cohort study of biomedical laboratory workers was conducted to examine whether the excess cancer morbidity that we found can be explained by exposure to a particular group of substances, taking into consideration potential confounders.

Methods: The study population included 163 cases and two matched control groups: laboratory workers (311) and general population (448) workers.

Results: Multiple conditional regression analysis showed that working in research laboratories involved an increased risk of cancer generally among women [risk ratio 2.

Cancer incidence among laboratory workers in biomedical research and routine laboratories in Israel: Part I-the cohort study.

Background: Laboratory work is associated with exposure to a mixture of carcinogens.

Methods: The cohort is comprised of 4,300 laboratory workers. Cancer incidence was followed from 1960 to 1997.