Publications by authors named "R Gueneau"
Article Synopsis
- Campylobacteriosis is the leading bacterial cause of diarrhea in kidney transplant recipients (KTRs), but risk factors for this infection remain unclear.
- A 10-year study in France identified 326 KTRs with campylobacteriosis, revealing an incidence rate of 2.3 cases per 1,000 patient-years, primarily occurring around 2.4 years after transplantation.
- The main risk factors for developing campylobacteriosis include the use of corticosteroids, acute rejection episodes, low lymphocyte counts, and low estimated glomerular filtration rate (eGFR); treatment should prioritize azithromycin due to high resistance to fluoroquinolones.
Background: Aspergillus spp. is an uncommon and life-threatening cause of transplantrenal artery pseudoaneurysm after kidney transplantation.
Case: We report the case of a 62-year-old woman who underwent kidney transplantation 10 months before and presented a 7-cm asymptomatic transplant renal artery pseudoaneurysm.
Article Synopsis
- Therapeutic monoclonal antibodies have been developed to treat severe cases of COVID-19 by targeting the Spike protein of the virus, SARS-CoV-2, but can lead to mutations in the virus.
- A case study is presented of an immunosuppressed patient with a B.1.1.7 variant who received these treatments and developed three specific mutations in the Spike protein: K417N, E484K, and Q493R.
- The findings emphasize the need for careful monitoring of virus mutations in patients on monoclonal antibody therapy to improve infection management and prevent variant transmission.