Publications by authors named "R Grunow"

Article Synopsis
  • The study aimed to establish standardized methods for antimicrobial susceptibility testing of Bacillus anthracis across Europe, addressing the absence of clinical breakpoints from EUCAST.
  • About 335 B. anthracis isolates were tested using two methodologies, revealing wild-type distributions and defined epidemiological cut-off values (ECOFFs) for ten key antimicrobials.
  • Results showed resistance in some strains, with implications for monitoring resistance development and the need for further genetic investigations on isolates exhibiting slightly increased minimum inhibitory concentrations (MICs).
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Brucellosis, mainly caused by (B.) , is associated with a risk of chronification and relapses. Antimicrobial susceptibility testing (AST) standards for are not available, and the agent is not yet listed in the EUCAST breakpoint tables.

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In November 2018, a tularaemia outbreak occurred in Bavaria, Germany, among participants of a hare hunt and butchery employees handling the hares. We conducted an epidemiological outbreak investigation, including a retrospective cohort study among hunting participants, to identify likely transmission routes and activities associated with infection. Twelve of 41 participants were antibody-positive for Francisella (F.

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The cascade of innovations in biotechnology opens new pathways for biological warfare. The international laboratory network being developed under the UN Secretary-General’s Mechanism could provide vital evidence in case of an alleged biological attack.

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