Publications by authors named "R Groote Veldman"
Lanreotide versus placebo for tumour reduction in patients with a Ga-DOTATATE PET-positive, clinically non-functioning pituitary macroadenoma (GALANT study): a randomised, multicentre, phase 3 trial with blinded outcome assessment.
Lancet Reg Health Eur
July 2024
Background: No established medical treatment options currently exist for patients with non-functioning pituitary macroadenoma (NFPMA). Somatostatin analogues may prevent tumour growth, but randomised controlled trials are lacking. somatostatin receptor assessment with Ga-DOTATATE PET could help in selecting patients for treatment.
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- * Cobra venom leads to a decrease in heart muscle's contractile force, while rattlesnake venom increases both the strength and frequency of heart contractions.
- * The findings demonstrate distinct and complex effects of snake venoms on heart function, emphasizing the varying impacts on heart cell structure.
Background: Broadcast media is a method to communicate health information to the general public and has previously been used in prior public health emergencies. Despite the current ubiquity of social media, traditional news programming retains relatively large audiences, which increased during the COVID-19 pandemic's early days. Viewership of broadcast media networks' evening news skews toward older groups (age 65 and up) which were vulnerable to health complications related to the COVID-19 pandemic.
View Article and Find Full Text PDFPurpose: Clinically non-functioning pituitary macroadenomas (NFMA) have been reported to express somatostatin receptors (SSTR), but results are inconsistent across different studies. This may be related to limited sensitivity and specificity of techniques used to date, i.e.
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- A study was conducted to evaluate the effectiveness of two α-adrenergic receptor blockers, phenoxybenzamine and doxazosin, in preventing hemodynamic instability during surgery for pheochromocytoma or sympathetic paraganglioma.
- The results showed no significant difference in the time patients spent outside the target blood pressure range when treated with either medication, but phenoxybenzamine was linked to better management of intraoperative hemodynamic stability.
- Overall, both drugs were safe with no mortality reported, and the complication rates were similar, highlighting the importance of individualized patient care in surgical settings.