Publications by authors named "R Grifoni"

This study examines the results of autopsy examinations specifically aimed at documenting complications arising from the implantation phase and treatment with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in patients with refractory cardiac arrest. ECMO and VA-ECMO in particular are life-saving interventions that, in the case of cardiac arrest, can temporarily replace cardiac pump function. VA-ECMO is, however, a very invasive procedure and is associated with early mechanical, haemorrhagic, and thrombotic events, infections, and late multi-organ dysfunction.

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  • Melanoma cases are on the rise among young people, with many patients experiencing high levels of anxiety and depression linked to their body image and overall quality of life.
  • A study of 73 advanced melanoma patients found those with skin metastasis had worse body image, while anxiety and depression levels were similar regardless of cancer stage.
  • Patients on targeted therapy reported lower anxiety and depression compared to those on immunotherapy, highlighting different impacts of treatment on mental health.
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  • Child abuse is often underestimated, leading to challenges for healthcare professionals and forensic pathologists in accurately diagnosing cases, especially when injuries mimic signs of abuse but have different causes.* -
  • A study identified six instances (1.43%) of injuries initially thought to be abuse, which were later determined to be due to alternative medical practices or specific medical conditions following thorough examination by a multidisciplinary team.* -
  • Awareness of "mimics" is vital for professionals to prevent diagnostic errors and ensure children receive the appropriate medical care, highlighting the need to differentiate between actual abuse and conditions caused by non-medical practices.*
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Solitary primary extraosseous plasmacytoma is a rare disease in the gastrointestinal tract, recently classified as an "exceptional" tumor of the colon site. The real incidence (one case/population/year) is unknown but reasonably less than 1/10,000,000 cases/year with very few descriptions in the literature. The rare cases described in the literature are often diagnosed after surgery for perforation and with predominant localization of the left colon.

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Background: Post-mortem toxicology constantly deals with the research of reliable alternative matrices to be applied in case of highly damaged corpses (such us carbonized, skeletonized, human remains, etc.). Teeth represent a promising alternative matrix since dental tissues are endowed by different features, resistance and stability after death.

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