[Mechanisms of respiratory system lesions in chemical plant workers of the environmental protection department in comparison with workers of pesticide producing departments].

In chemical plant workers producing pesticides chronic bronchitis and disturbed pulmonary ventilation are frequent. The aim of the examination of the staff (sewage-treatment plant, waste combustion plant, waste storage, industrial water pumping station)--16 males aged 21-53 years--was to assess: 1. Connective tissue metabolism--serum concentration of type I and III procollagen propeptides, collagen I telopeptide, hydroxyproline, alpha1-AP and alpha2-M antiproteases, interstitial collagenase (MMP-1) activity, as well as urine hydroxyproline and desmosine.

Blood antioxidant parameters in patients with diabetic retinopathy.

It has been postulated that enhanced generation of reactive oxygen species (ROS) may take part in a pathogenesis of diabetic microvascular complication - retinopathy. There are two types of diabetic retinopathy, non-proliferative (simplex) and proliferative. ROS are anihilated by an intracelluar enzymatic system composed mainly of glutathione peroxidase (GPx), superoxide dismutase (SOD) and catalase (CAT).

Decreased red blood cells deformability in acute pancreatitis in the rat. Effect of tirilazad mesylate.

Unlabelled: The ability of erythrocytes to deform is the key feature in maintain the microcirculation. Both acute pancreatitis and decrease in deformability of erythrocytes are associated with increase in lipid peroxidation as a result of excess production of free radicals. Hence the aim of this study was to investigate the red blood cell (RBC) deformability and lipid peroxidation product content within erythrocytes in acute pancreatitis in rats.

Red blood cells deformability and oxidative stress in acute pancreatitis.

The aim of this study was to evaluate the RBC deformability and oxidative stress parameters during acute pancreatitis. Healthy volunteers and patients with mild or severe acute pancreatitis were evaluated. There were no changes in erythrocyte's deformability in patients with mild acute pancreatitis.