Fabrication of hafnium-based nanoparticles and nanostructures using picosecond laser ablation.

This work presents a unique and straightforward method to synthesise hafnium oxide (HfO) and hafnium carbide (HfC) nanoparticles (NPs) and to fabricate hafnium nanostructures (NSs) on a Hf surface. Ultrafast picosecond laser ablation of the Hf metal target was performed in three different liquid media, namely, deionised water (DW), toluene, and anisole, to fabricate HfO and HfC NPs along with Hf NSs. Spherical HfO NPs and nanofibres were formed when Hf was ablated in DW.

Dual Mini-Fragment Plate Fixation of Midshaft Clavicle Fractures Demonstrates Fewer Union Complications but Similar Patient-reported Outcomes Compared to Nonoperative Management: A Cohort Study with Mean 3.4 Year Follow-Up.

Purpose: Although open reduction and internal fixation (ORIF) is the gold standard treatment for displaced midshaft clavicle fractures, recent studies have advocated for nonoperative management, citing high rates of reoperation associated with operative intervention. However, no studies have compared nonoperative management to ORIF with dual-plate fixation, which may be associated with lower rates of reoperation compared to single-plate fixation. The purpose of this study was to compare the complications and patient-reported outcomes of dual mini-fragment plate fixation to nonoperative management for displaced midshaft clavicle fractures.

Intraoperative Molecular Imaging With Pafolacianine: Histologic Characteristics of Identified Nodules.

Background: With increased early detection efforts, surgery for early-stage lung cancer is expected to rise. Pafolacianine is the first FDA approved targeted optical imaging agent indicated as an adjunct for intraoperative identification of malignant and nonmalignant pulmonary lesions in adult patients with known or suspected cancer in the lung.

Methods: This is a retrospective review of the malignant and nonmalignant lesions identified by pafolacianine with intraoperative molecular imaging (IMI) in the multi-center Phase 2 and Phase 3 ELUCIDATE clinical trials.

Potassium Nitrate in Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial.

Importance: Nitric oxide deficiency may contribute to exercise intolerance in patients with heart failure with preserved ejection fraction (HFpEF). Prior pilot studies have shown improvements in exercise tolerance with single-dose and short-term inorganic nitrate administration.

Objective: To assess the impact of chronic inorganic nitrate administration on exercise tolerance in a larger trial of participants with HFpEF.

Infertility care and physician trainees: a survey on elective fertility preservation.

Purpose: Female physicians experience a higher rate of infertility than the general population, are more likely to delay childbearing in training and use assisted reproductive technologies. Little is known about how physician trainees use infertility services or perceive an employer-sponsored fertility preservation benefit. This study assessed physician trainee knowledge of and experiences with infertility and gauged interest in an employer-sponsored fertility preservation benefit.