Exploring the potential of malononitrile functionalized donor-acceptor systems for non-volatile memory device applications.

A novel series of D-bridge-A type organic small molecules has been designed, synthesized, and evaluated for non-volatile resistive switching write-once read-many (WORM) memory application. This study explores structure-property relationships by coupling electron-deficient malononitrile units with donors such as dibenzofuran, dibenzothiophene, and triphenylamine. Photophysical investigations revealed significant intramolecular charge transfer interaction, while electrochemical analyses demonstrated optimal band gaps ranging from 2.

TFA-promoted (hetero)arylation/hydroxylation of quinoxaline-2-one derivatives with electron-rich aromatic compounds.

A metal- and solvent-free, one-pot and TFA-promoted method for the construction of hetero/aryl-substituted quinoxalin-2-ones, pyrazin-2(1)-ones, and pyrimidin-4(3)-ones is reported. This method involves the reaction of chloro-derivatives of nitrogen heterocycles with electron-rich arenes/heteroarenes, followed by hydroxylation. This protocol is easy to use, providing access to (hetero)aryl-substituted -heterocycles in good yields.

Modeling the Current and Future Distribution of (Roxb.) Suksathan & Borchs.: A Monotypic Plant Endemic to the Western Ghats-Sri Lanka Biodiversity Hotspot.

Species distribution modeling (SDM) is an essential tool in ecology and conservation for predicting species distributions based on species presence/absence data and environmental variables. The present study aimed to understand the distribution pattern and habitat suitability of under current and future climate change scenarios (2050 and 2070) using and tools. The study also intended to identify key environmental predictors of distribution.

Effect of low high dietary-advanced glycation end products on insulin-sensitivity and inflammatory- markers among overweight/obese Asian-Indian adults-A randomised controlled trial.

The present study investigated the effect of low high-dietary-Advanced Glycation End products-based diets on oral disposition index-(DIo)-a marker of islet β-cell function and cardiometabolic risks factors in 38-overweight and obese Asian Indian-adults (aged 25-45 years with body-mass-index (BMI) ≥23kg/m) through 12-week isocaloric crossover feeding trial. Biochemical-measures included-glucose tolerance test (GTT), Insulin assay (0,30 and 120 min), lipid-profile, serum-adiponectin, serum-AGE and serum-Thiobarbituric acid reactive substances-(TBARS) assessed both at baseline and end of each intervention. Generalised linear models showed that low-dAGE diet significantly improved in oral disposition index [Least Square Mean (SE), +0.

Netrin 1 as a biomarker in cancer: scoping diagnostic, prognostic, and therapeutic perspectives with a focus on oral squamous cell carcinoma.

Goal of the review: The utilization of biomarkers to predict cancer risk, prognosis, and treatment outcomes is paramount. Netrin-1 (NTN1), known for its role in commissural axon guidance during embryonic development, has emerged as a versatile molecule with significant implications in cancer and neurobiology. Structurally resembling laminin, Netrin-1 regulates neuronal connectivity and plasticity in adulthood, influencing axonal and dendritic growth, neurotransmission, and cell migration.