Publications by authors named "R Garcia Tenorio"
Article Synopsis
- This study aimed to evaluate the effectiveness of the Actigraph and Xiaomi Smart Band in counting steps for individuals recovering from a stroke, focusing on their validity and accuracy.
- Fifty stroke patients took part in the 2-min Walk Test while wearing both devices, allowing researchers to compare the actual step counts with those estimated by the monitors.
- Results showed that while the Actigraph had low accuracy, the Xiaomi Smart Band demonstrated good validity and accuracy, making it an affordable option for tracking steps post-stroke.
Transmission electron microscopy significantly contributed to unveil the course of virus entry, replication, morphogenesis, and egress. For these studies, the most widely used approach is imaging ultrathin sections of virus-infected cells embedded in a plastic resin that is transparent to electrons. Before infiltration in a resin, cells must be processed to stabilize their components under the observation conditions in an electron microscope, such as high vacuum and irradiation with electrons.
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- Previous research of DNA and chromosome data has shown significant genetic diversity within the Physalaemus cuvieri - Physalaemus ephippifer species complex of frogs in South America, identifying seven major genetic lineages.
- The study analyzed various genetic data to explore the relationship between P. ephippifer and P. cuvieri Lineage 1, finding signs of genetic mixing and chromosome evolution.
- It highlights the role of chromosome divergence and hybridization in the evolutionary history of these frogs, particularly in influencing sex chromosome evolution in amphibians.
Article Synopsis
- Next-generation sequencing (NGS), including targeted panels, exome sequencing, and genome sequencing, is becoming an important tool for diagnosing hereditary ataxia (HA), and understanding its diagnostic yield (DY) is vital for effective clinical choices.
- A systematic review of studies from 2016 to 2022 revealed a median DY of 43%, with targeted panels achieving 46% and exome sequencing 41.9%, showing that DY is influenced by specific symptoms, parental consanguinity, and inheritance patterns.
- ES is viewed as more beneficial since it allows for the examination of rare genes not considered in targeted panels, and there’s a noticeable difference in DY based on prior genetic testing, investments in specific gene panels,
Transmission electron microscopy (TEM) has been essential to study virus-cell interactions. The architecture of viral replication factories, the principles of virus assembly and the components of virus egress pathways are known thanks to the contribution of TEM methods. Specially, when studying viruses in cells, methodologies for labeling proteins and other macromolecules are important tools to correlate morphology with function.
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