Sirolimus for vascular anomalies in the first year of life: a systematic review.

Evidence on effectiveness and safety of sirolimus in congenital vascular anomalies in infancy is lacking. We aim to systematically review the efficacy and safety of sirolimus in treating congenital VA in infancy. We searched for and included all studies evaluating sirolimus for VA in the first year of life.

A 48-Year-Old Man with Fevers and Weight Loss.

A 48-Year-Old Man with Fevers and Weight Loss48-year-old man presented for evaluation of fevers, night sweats, and a 20-pound unintentional weight loss over 3 months. He also had a dry cough over the same time, without dyspnea, chest discomfort, or hemoptysis. On examination, he was febrile and tachycardic, with tenderness in the right upper quadrant on abdominal palpation.

Caloric Stimulation with Water and Air: Responses by Age and Gender.

Introduction: The caloric test is a well-known valuable clinical instrument that can evaluate and quantify the functional status of both lateral semicircular canals. The American National Standard Institute (ANSI) does not include air as a standard method for caloric stimulation due the lack of published data to determine response variability comparable to water. Due the controversy about air irrigators, it is worthwhile to evaluate the presence of differences between the two irrigation methods in caloric response.