When trauma bites back: a systematic review on direct orofacial macrotrauma and temporomandibular disorders.

Objectives: Temporomandibular disorders (TMD) are musculoskeletal conditions with a multifactorial aetiology. The predictive role of direct orofacial macrotrauma in the development of TMD is considered controversial. This systematic review aims to elucidate the association between direct orofacial macrotrauma and TMD, and to identify potential factors involved in this relationship.

OligoDistiller: A Platform Agnostic Software Tool for MS and MS Data Analysis of Complex Oligonucleotides and Their Impurities.

Oligonucleotides are currently one of the most rapidly advancing classes of therapeutic modalities. Understanding critical quality attributes, such as the impurity profile, stability, potential metabolites, and sequence conformity, is the key to their ultimate success. To obtain the information presented above, liquid chromatography-mass spectrometry (LC-MS) is often employed.

Developing and Improving Personality Inventories Using Generative Artificial Intelligence: The Psychometric Properties of a Short HEXACO Scale Developed Using ChatGPT 4.0.

In the current study, we investigated the utility of generative AI for survey development and improvement. To do so, we generated a 24-item HEXACO personality inventory using ChatGPT 4.0, the ChatGPT HEXACO inventory (CHI), and investigated whether ChatGPT could modify the CHI to either improve its internal consistency or its content validity.

The effect of early warning scoring systems on adverse outcome in surgical patients: A systematic review.

Background: An early warning scoring system aims to detect clinical deterioration at an early stage and prevent failure-to-rescue in hospitalized patients. In this systematic review we studied the effect of an early warning scoring system on adverse outcome in surgical patients.

Methods: This review was conducted and reported according to PRISMA and the protocol of this review is registered at PROSPERO, under the registration number CRD42018107799.

Targets of influenza human T-cell response are mostly conserved in H5N1.

Frequent recent spillovers of subtype H5N1 clade 2.3.4.