Participant recruitment and retention in randomised controlled trials of melanoma surveillance: A scoping review.

Background: This scoping review aims to collate and describe data on recruitment, retention, and strategies used to improve these, in randomised controlled trials of melanoma surveillance.

Methods: We searched MEDLINE, EMBASE, CINAHL and CENTRAL databases from inception until October 23, 2023. Two reviewers screened titles and abstracts, and full-texts, and one reviewer extracted data (convenience sample (n = 5) checked by a second).

Best practice in high-frequency water quality monitoring for improved management and assessment; a novel decision workflow.

The use of high-frequency water quality monitoring has increased over several decades. This has mostly been motivated by curiosity-driven research and has significantly improved our understanding of hydrochemical processes. Despite these scientific successes and the growth in sensor technology, the large-scale uptake of high-frequency water quality monitoring by water managers is hampered by a lack of comprehensive practical guidelines.

Is there a difference in ischaemic heart disease deaths that occur without a preceding hospital admission in people who live in rural compared with urban areas of Aotearoa New Zealand? An observational study.

Objectives: Unlike comparable countries, acute coronary syndrome (ACS) mortality is similar among patients who present to rural and urban hospitals in Aotearoa New Zealand (NZ). The aim of this study was to determine whether differences in ischaemic heart disease (IHD) deaths that occurred without a preceding hospital admission in rural and urban populations explained this finding.

Design: Retrospective observational study using the National Mortality Collection (MORT) and National Minimum Dataset (NMDS) for hospital discharges datasets.

Evaluating the Benefits and Limits of Multiple Displacement Amplification With Whole-Genome Oxford Nanopore Sequencing.

Multiple displacement amplification (MDA) outperforms conventional PCR in long fragment and whole-genome amplification, making it attractive to couple MDA with long-read sequencing of samples with limited quantities of DNA to obtain improved genome assemblies. Here, we explore the efficacy and limits of MDA for efficient low-cost genome sequence assembly using Oxford Nanopore Technologies (ONTs) rapid library preparations and minION sequencing. We successfully generated almost complete genome sequences for all organisms examined, including Gram-positive (Staphylococcus aureus, Enterococcus faecium) and Gram-negative (Escherichia coli) prokaryotes and one challenging eukaryotic pathogen (Cryptosporidium spp) representing a broad spectrum of critical infectious disease pathogens.