Multiplexed Assays of Variant Effect and Automated Patch Clamping Improve -LQTS Variant Classification and Cardiac Event Risk Stratification.

Background: Long QT syndrome is a lethal arrhythmia syndrome, frequently caused by rare loss-of-function variants in the potassium channel encoded by . Variant classification is difficult, often because of lack of functional data. Moreover, variant-based risk stratification is also complicated by heterogenous clinical data and incomplete penetrance.

Community Health Workers: Bridge to Pediatric Mental Health Equity.

We currently face a national crisis in youth mental health and well-being and significant child behavioral health inequities. There is a growing recognition among health care institutions, policymakers, researchers, and communities that major health problems of our time, including this crisis, must be confronted by addressing the underlying "causes of the causes," or social determinants of health. Social determinants of health are defined by the US Centers for Disease Control and Prevention as the conditions in which people live, learn, work, play, worship, and age and highlight the role that power and privilege occupy in shaping societal access to these resources.

Multiplexed Assays of Variant Effect and Automated Patch-clamping Improve -LQTS Variant Classification and Cardiac Event Risk Stratification.

Background: Long QT syndrome (LQTS) is a lethal arrhythmia syndrome, frequently caused by rare loss-of-function variants in the potassium channel encoded by . Variant classification is difficult, often owing to lack of functional data. Moreover, variant-based risk stratification is also complicated by heterogenous clinical data and incomplete penetrance.

Public health benefits of zero-emission electric power generation in Virginia.

Curbing the worst impacts of global climate change will require rapidly transitioning away from fossil fuel across all sectors of the economy. This transition will also yield substantial co-benefits, as fossil fuel combustion releases harmful pollutants into the air. In this article, we present an analysis of the co-benefits to health and health-care costs related from decarbonization of the power sector, using the Virginia Clean Economy Act (VCEA) as a case study.