Intermediate scattering function of a gravitactic circle swimmer.

We analyze gravitaxis of a Brownian circle swimmer by deriving and analytically characterizing the experimentally measurable intermediate scattering function (ISF). To solve the associated Fokker-Planck equation, we use a spectral-theory approach, finding formal expressions in terms of eigenfunctions and eigenvalues of the overdamped-noisy-driven pendulum problem. We further perform a Taylor series of the ISF in the wavevector to extract the cumulants up to the fourth order.

Adipose-derived mesenchymal stromal cells: A study on safety and efficacy in ocular inflammation.

Purpose: This study explores the application of adipose-derived mesenchymal stromal cells (adMSCs) as a therapy for ocular inflammatory diseases utilizing a chronic GVHD model.

Methods: Human adMSCs were administered via subconjunctival injection into mice with chronic ocular GVHD. Clinical scores and changes in T cell populations were analyzed.

The Palliative Arts: Envisioning a New Paradigm in Palliative Care.

A growing body of evidence supports the effectiveness of arts-based interventions in nurturing human connection, healing, and reflection-for patients living with illness, their families, and their health care communities. Thus, we propose that these interventions, what we call the Palliative Arts-just as much as science-should be systematically integrated in clinical education, practice, research, wellness, leadership, and advocacy to impact person-centered outcomes. Our interprofessional team describes a variety of arts-based programming that its authors are leading to highlight the breadth of existing Palliative Arts work and point to future horizons for its integration in health care education and clinical settings.

The Palliative Story Exchange: An innovative storytelling intervention to build community, foster shared meaning, and improve sustainability.

Objective: Palliative care (PC) faces a workforce crisis. Seriously ill patients surpass the supply of PC cliniciansin their work clinicians face repeated loss and extreme suffering which can have deleterious consequences, such as burnout and attrition. We urgently need interventions that foster thriving communities in this emotionally complex environment.

Effects of temporal IFNγ exposure on macrophage phenotype and secretory profile: exploring GMP-Compliant production of a novel subtype of regulatory macrophages (Mreg) for potential cell therapeutic applications.

Background: Macrophages are involved in tissue homeostasis, angiogenesis and immunomodulation. Proangiogenic and anti-inflammatory macrophages (regulatory macrophages, Mreg) can be differentiated in-vitro from CD14 monocytes by using a defined cell culture medium and a stimulus of IFNγ.

Aim Of The Study: To scrutinize the potential impact of temporal IFNγ exposure on macrophage differentiation as such exposure may lead to the emergence of a distinct and novel macrophage subtype.