Publications by authors named "R G Pullen"

Appendiceal cancer (AC) is a rare malignancy, occurring in 1 to 2 individuals per million annually in the US. It is often diagnosed incidentally during appendectomies or imaging for unrelated conditions. This article explores the risk factors, clinical presentation, diagnostic methods, pathology, staging, and treatment options for AC, highlighting disparities in access to care across different demographics.

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Article Synopsis
  • Transcriptomics is about studying RNA, which tells us how genes work in different cells or organisms.
  • Community transcriptomics looks at RNA from different organisms living together to see how they interact.
  • This review talks about the new methods to study transcriptomics and how they can help with community transcriptomics, even though there are some challenges in the process.
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Background: Prior exacerbation history is used to guide initial maintenance therapy in COPD; however, the recommendations were derived from patients already diagnosed and treated.

Methods: We assessed the rates of moderate ( treated with antibiotics and/or systemic corticosteroids) and severe ( hospitalised) exacerbations in the year following diagnosis in patients newly diagnosed with COPD according to their prior history of exacerbations, blood eosinophil count (BEC) and whether maintenance therapy was started. Data were extracted from the Optimum Patient Care Research Database.

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Ovarian cancer, a leading cause of cancer deaths, poses challenges due to insidious development and vague signs and symptoms. Risk factors include age, reproductive history, genetic mutations, and environmental factors. Treatment involves surgery, chemotherapy, and targeted therapy, with nursing interventions focusing on symptom management and supportive care.

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