Creutzfeldt - Jakob disease: clinical cases.

A 68 y.o. woman delivered to the emergency department with severe speech impairment in a somnolent state - 13 points Glasgow Coma Scale.

[Interrelation between levels of eicosanoids and tachykinins in the expired air condencate in the obstructive type respiratory insufficiency in patients with destructive pulmonary tuberculosis].

The content was studied of vasoactive intestinal peptide (VIP), substantia P (SP), bombesine (BMB), prostaglandins (PG) E2, F2alpha, 6-keto-F1alpha, Tx A2, and leukotrien (LT) B4 in the expired air condensate with the aid of the radioimmune technique to reveal a relation between pulmonary tachykinins and eicosanoids in obstructive type respiratory incompetence in patients with pulmonary tuberculosis. In patients with pulmonary tuberculosis, a high level of BMB was measurable in the expired air condensate. A linear negative correlation has been established between BMB content and forced expiratory volume, SP and respiratory volume, SP and lung capacity.

[Endoscopic characteristics of chronic bronchitis treated with substitution of surfactant].

An analysis has been performed of endoscopic management of chronic bronchitis with making use of substitution surfactant therapy with a home-produced drug preparation of the exogenous surfactant sucrim. Positive results obtained in the studies conducted permit the substantiation of a 2-fold use of the above drug in a combined treatment. Visual normalization of bronchial mucosa in purulent diffuse endobronchitis, degree III intensity of inflammation, was seen by day 8 to 12 from the commencement of therapy.

[Use of food additives in a multimodal treatment of disseminated pulmonary tuberculosis].

Effects have been studied of multimodality treatment on the function of external breathing in patients with disseminated pulmonary tuberculosis using food additives Trace Minerals. Positive dynamics has been recordable of changes in indices for forced lung vital capacity, minute oxygen consumption, both prior and after loading, and maximum volume speed (MVS75) before loading. The obtained data are indicative of the efficacy of using vitamin-mineral additives Trace Minerals evidenced by improvement in bronchial patency and normalization of ventilation-and-perfusion relations in patients with destructive forms of pulmonary tuberculosis.

[Correction of pulmonary moisture exhalation in patients with tuberculosis of the respiratory organs].

It has been found out that in patients with tuberculosis of the respiratory organs the moisture-discharging function of the lungs is impaired, its degree resting with the clinical form of tuberculosis, site, extension, and phase of the process. In patients with disseminated tuberculosis in the phase of infiltration and in those with infiltrative tuberculosis, moisture discharge copious whereas in patients with chronic forms of tuberculosis it is meagre. In those patients presenting with freshly detected forms of tuberculosis the proposed method involving inhalations with broncholytic mixture and glucocorticoids designed to correct the impaired moisture-discharging function of the lungs has been shown to return the pulmonary moisture discharge back to normal one month earlier than in controls.