Publications by authors named "R G Oshima"
The self-consistent field (SCF) procedure is the standard technique for solving the Hartree-Fock and Kohn-Sham density functional theory calculations, while convergence is not theoretically guaranteed. Direct minimization methods, such as the augmented Lagrangian method (ALM) and second-order SCF (SOSCF), obtain the SCF solution by minimizing the Lagrangian with the gradient. In SOSCF, molecular orbitals are optimized by truncating the Taylor expansion of a unitary matrix represented in exponential form to ensure the orthonormality condition.
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- The PPAR Stroke study investigated pemafibrate's effectiveness in slowing down cerebrovascular atherosclerosis in stroke patients with high triglycerides, involving 99 participants over a 2-year period.
- Results showed significant reductions in triglyceride and inflammatory marker levels, with some improvement in carotid artery thickness, particularly on the left side.
- The findings suggest that pemafibrate may have beneficial effects on lipid profiles and inflammation, potentially aiding in the management of atherosclerotic diseases following a stroke.
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- Kpna4 knock-out (KO) mice display behaviors linked to psychiatric disorders, including anxiety, social interaction issues, and sensorimotor gating problems.
- Contrary to expectations, Kpna4 deficiency leads to increased expression of NF-κB and proinflammatory cytokines, indicating heightened inflammatory responses in the brain areas examined.
- Additional findings suggest that the absence of Kpna4 may enhance polycomb repressor complex 2 (PRC2) activity in glial cells, further contributing to the observed behavioral deficits.
The effect of baseball grips on the hardness of the flexor digitorum superficialis.
J Sports Med Phys Fitness
November 2024
Background: In baseball pitches, the forkball requires a special grip, pinching the ball between the second and third fingers to achieve the resulting breaking ball trajectory. We hypothesized that the forkball grip would have a substantial impact on the hardness of the flexor digitorum superficialis. The aim was to quantify and clarify the change in the hardness of the flexor digitorum superficialis due to the forkball grip.
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