[Morbidity and prophylaxis of hemorrhagic fever with renal syndrome in the Republic of Bashkortostan].

The brief retrospective analysis of morbidity, epizootological data and preventive measures with respect to haemorrhagic fever with renal syndrome (HFRS) during the whole period of its registration on the territory of the Republic of Bashkortostan along with the structure of HFRS morbidity during epidemic seasons of 1998 and 1999 is presented. The main causes of decreased HFRS morbidity in 1998, its rise in 1999 as well as prognosis for the year 2000 were detected. The level of HFRS morbidity among the population was found to be directly related to the number of rodents and their infection rate.

[An epidemiological analysis of hemorrhagic fever with renal syndrome morbidity in the Republic of Bashkortostan in 1997].

The outbreak of hemorrhagic fever with renal syndrome (HFRS) in the Republic of Bashkortostan, resulting in 10,057 registered cases of the disease (287 cases per 100,000 of the population), was analyzed. HFRS cases among the population were registered in 52 out of 54 regions of Bashkortostan. 31% of the total number of patients were the inhabitants of rural regions (170 cases per 100,000) and 69% were urban dwellers (295 cases per 100,000), mainly in Ufa (512 cases per 100,000).

[The intensity of the immune response to the hemorrhagic fever with renal syndrome virus among different population groups of Bashkortostan].

For the first time the natural immune stratum to hemorrhagic fever with the renal syndrome (HFRS) among the population of all regions of Bashkiria, a large territory with the highest morbidity level in this infection in the USSR, was studied. 9,176 persons over 15 years of age were examined by radioimmune techniques. Analysis of the immune structure of the population revealed that the share of immune males was higher than that of immune females, but the difference was less than the difference between males and females among the registered HFRS patients.

[Effect of weather conditions in an epidemic season on the nature of the morbidity of hemorrhagic fever with renal syndrome].

The epidemic manifestation of the most active natural foci of HFRS in the USSR on the territory of Bashkiria is described. The authors compare two epidemic seasons of 1975-1976 and 1977-1978. Besides the number of rodents, the rise of morbidity is influenced by their early multiplication and weather conditions.

Antibodies to the HFRS virus in the human population of European RSFSR as detected by radioimmunoassay.

Natural immunity to the causative agent of hemorrhagic fever with renal syndrome (HFRS) has first been studied using radioimmunoassay (RIA) in the human population of the Bashkir ASSR with the highest incidence of this infection and of five other regions of the RSFSR with lower incidence of HFRS. The antigen was prepared as a suspension of lungs of rodent from natural HFRS foci and contained a high concentration of virus protein. 12,000 sera from the population of 6 areas of the RSFSR were examined.