Modulation of Autophagy and Nitric Oxide Signaling via Glycyrrhizic Acid and 7-Nitroindazole in MPTP-induced Parkinson's Disease Model.

Background: Parkinson's disease (PD) is characterized by dopaminergic (DA) neuron loss, Lewy body build-up, and motor dysfunction. One of the primary pathogenic mechanisms of PD development is autophagy dysfunction and nitric oxide-mediated neurotoxicity.

Purpose: The current study focuses on autophagy and nitric oxide (NO) signaling roles in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-intoxicated PD mice and their protection by their modulators.

Chronic pulmonary aspergillosis in tea population of Assam.

Background: Chronic pulmonary aspergillosis (CPA) is a disease commonly caused by Aspergillus fumigatus and other Aspergillus species characterized by cavitary lung lesions. Tea garden population is an agrarian population of Assam, mostly associated with tea plantations. Assam is a major tea-producing state with 803 tea gardens producing approximately 50% of the total tea in India, of which 177 are present in the Dibrugarh district alone.

Anti-Aging Effect of Traditional Plant-Based Food: An Overview.

Aging is a complex process that involves many physiological mechanisms that gradually impair normal cellular and tissue function and make us more susceptible to diseases and death. It is influenced by intrinsic factors like cellular function and extrinsic factors like pollution and UV radiation. Recent scientific studies show that traditional plant-based foods and supplements can help mitigate the effects of aging.

Antibiofilm activity of exopolysaccharide-mediated ZnO nanoparticle against Pseudomonas aeruginosa biofilm.

Exopolysaccharides (EPSs) are the group of biological macromolecules those play a potent role in protecting the bacteria from any sorts of stress. They exhibit multifunctional roles in natural and bioactive product science hence exhibits various types of medical and biochemical applications. EPS ensures the storage of nutrients, produce antigens to create defense mechanism during infection, and is also responsible for the formation of biofilm and cell adhesion.

Quantum spin-liquid in BaCuSbOepitaxial thin films.

Hexagonal perovskite materials are emerging quantum spin liquid (QSL) systems providing a fertile ground to realize novel quantum phenomena. The epitaxially grown thin films of such materials offer a compelling approach to utilize exotic quantum phases for device applications with better control over the structure. We fabricate the intriguing QSL triple perovskite BaCuSbOepitaxially onto a MgO (100) substrate by pulsed laser deposition technique as well as in bulk form for comparison.