Publications by authors named "R G Masters"

Background: Whether elderly patients with aortic root or ascending aortic aneurysm (ATAA) would benefit from the new surgical size threshold of 5.0 cm is unknown. This study aimed to evaluate the natural history of ATAA in elderly patients and to compare long-term outcomes of those who underwent initial surveillance versus surgery.

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With limited evidence from intervention studies, causal relationships between motor competence and cognitive and social development have yet to be clearly established. In this research, we investigated whether a targeted training programme to improve fundamental movement skills (i.e.

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Article Synopsis
  • Current treatments for schizophrenia are inadequate, with no effective options for negative symptoms or cognitive issues, leading researchers to explore neuromodulation techniques like repetitive transcranial magnetic stimulation (rTMS) as a potential solution.
  • A systematic review and meta-analysis of rTMS studies involving schizophrenia found that while certain adverse effects (like headache and dizziness) were more common with active rTMS, the overall safety profile indicated no increased risk of severe side effects compared to sham treatments.
  • The study concludes that rTMS is safe and generally well-tolerated in people with schizophrenia, suggesting it does not pose a higher risk of adverse effects, including seizures, than seen in the general population.*
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Maintaining balance is a complex motor problem that requires coordinated contributions from multiple biological systems. Aging inevitably lessens the fidelity of biological systems, which can result in an increased risk of falling and associated injuries. It is advantageous to land safely, but falls manifest in diverse ways, so different motor solutions are required to land safely.

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Quaternary ammonium compound (QAC) disinfectants represent one of our first lines of defense against pathogens. Their inhibitory and bactericidal activities are usually tested through minimum inhibitory concentration (MIC) and time-kill assays, but these assays can become cumbersome when screening many compounds. We investigated how the dynamic surface tension (DST) measurements of QACs correlate with these antimicrobial activities by testing a panel of potent and structurally varied QACs against the gram-positive Staphylococcus aureus and the gram-negative Pseudomonas aeruginosa.

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