Publications by authors named "R G Lagueruela"

Article Synopsis
  • The study aimed to assess if human fibrinogen concentrate could lower blood loss and the need for blood component therapy in neonate and infant patients undergoing cardiac surgery.
  • In a randomized trial with 30 pediatric patients, those receiving fibrinogen concentrate required significantly less cryoprecipitate than the placebo group.
  • While the treatment reduced cryoprecipitate use, it did not significantly affect overall blood loss or other measures of hemostasis and safety compared to the placebo.
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Article Synopsis
  • The study aimed to compare the effectiveness of liposomal bupivacaine (LB) and the ON-Q PainBuster pump in managing pain after cardiac surgery in children.
  • A total of 222 pediatric patients were analyzed, with LB patients receiving a higher dose of intravenous acetaminophen and more successful extubation compared to the ON-Q group.
  • While LB patients reported higher pain scores in the first 24 hours, overall, LB was found to be at least as effective as the ON-Q method for post-surgery pain relief.
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Background: In pediatric cardiac anesthesiology, there is increased focus on minimizing morbidity, ensuring optimal functional status, and using health care resources sparingly. One aspect of care that has potential to affect all of the above is postoperative mechanical ventilation. Historically, postoperative ventilation was considered a must for maintaining patient stability.

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Introduction: Rotational thromboelastometry (ROTEM) has been shown to reduce the need for transfused blood products in adult and pediatric cardiac surgery patients. However, similar evidence in newborns, neonates, and young infants is lacking. We quantified ROTEM value changes in pediatric patients on cardiopulmonary bypass (CPB) before, during and after blood product transfusion.

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This study evaluated whether rotational thromboelastometry (ROTEM; Tem International GmbH, Munich, Germany) FIBTEM maximum clot firmness (MCF) can be used to predict plasma fibrinogen level in pediatric patients undergoing cardiac surgery. Linear regression was conducted to predict plasma fibrinogen level using FIBTEM MCF (0.05 level of significance).

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