Publications by authors named "R G Krylova"

The subjects of the study were 1,249 primates of different species, kept in a nursery in the city of Adler. The subjects varied in age, were either clinically healthy, diseased, or dead (the death had been caused by an acute intestinal disease). Biological, molecular-genetic (PCR), and immunological (coagglutination reaction) methods were used in diagnostics of campilobacter infections.

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This paper presents the results of studies of a spontaneous viral infection in monkeys--encephalomyocarditis caused by encephalomyocarditis virus. The infection first detected in the Sukhumi Breeding Center in 1974 was observed in the Adler Breeding Center since 2001. The characteristics of the virus are described and principles of diagnostic by the results of pathologic studies are presented.

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The article contains an analysis of different mechanisms of persistent chronic venous insufficiency formation and its impact on the condition of lower extremity magistral vein wall. The authors studied autopsy samples of femoral vein segments from 86 patients aged 56 to 64 years, who had died of non-cardiovascular diseases. The investigation revealed significant changes in the vein wall structure, associated with persistent overload caused by valvular insufficiency and continuous persistent vertical reflux.

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Infectious diseases of monkeys, including the bacterial anthroponosous and zoogenous as well as viral infections, are described in the paper. A bulwark of research resulted from authors' independent long-term observations of monkey pathologies at Sukhumi and Adler primatological facilities. Pathologies are elucidated, which are better to be modeled in monkeys; there are also diseases that can be studied only in monkeys.

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The paper contains the results of a postmortem study of 461 cases of amyloidosis in monkeys of 4 species (Papio hamadryas, Macaca mulatto, Macaca fascicularis and Macaca nemestrina) from the Sukhumi and Adler primatological facilities. Emergence of amyloidosis was found to be dependent on age; the frequency ratio at which separate organs are affected is presented; the specific disease signs are described for different monkey species. Generalized and isolated cases of amyloidosis are elucidated with the liver being the most vulnerable organ in macaques (64%) and the kidneys--in baboons (94%).

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