Associated Factors and Causes of Chronic Disease Medication Oversupply.

Although medication oversupply results in waste of medications, triggers of medication oversupply remain unclear. This nationwide retrospective cohort study aimed to identify associated factors and causes of chronic disease medication oversupply in Japan by quantitative and qualitative analyses. Data of financial year 2019 from a large insurance claims database were used.

Impact of Regulatory Risk Communication on Thrombosis With Thrombocytopenia Syndrome for COVID-19 Adenovirus Vector Vaccines on European Healthcare Professionals.

Purpose: The European Medicines Agency (EMA) issued regulatory actions and communications in 2021 on thrombosis with thrombocytopenia syndrome (TTS) associated with adenovirus vector vaccines Vaxzevria or Jcovden. This study aimed to evaluate the impact of these actions on awareness, knowledge and implementation in practises of healthcare professionals (HCP).

Methods: Web-based cross-sectional surveys were conducted on HCPs engaged in the vaccination, monitoring or counselling about the vaccines.

Lifestyle factors as predictors of incident functional somatic disorder. Five-year follow-up of The DanFunD study.

Aims: To assess whether lifestyle factors, including sleep pattern, are predictors for the development of functional somatic disorder (FSD).

Methods: A population-based prospective cohort of 9656 men and women aged 18-76 years was established in 2011-2015 and invited for re-examination in 2017-2020, when 5738 participated. Median follow-up period was 65 months.