Publications by authors named "R G Hansford"
Background: Adults with intellectual or developmental disability (IDD) are at higher risk for incomplete cancer staging.
Aim: To compare unknown stage data between those with and without IDD.
Materials And Methods: We used the Ontario Cancer Registry linked to administrative health data between 2007 and 2019.
Article Synopsis
- Cancer significantly impacts individuals with intellectual or developmental disabilities (IDD), but there is limited research on their survival rates compared to those without IDD.
- A study in Ontario examined breast, colorectal, and lung cancer outcomes from 2007 to 2019, finding that people with IDD had much worse survival rates.
- The results showed that cancer patients with IDD had over twice the risk of dying from all causes and from cancer itself compared to those without IDD, highlighting the need for targeted interventions to address these survival disparities.
Background: Cancer is a leading cause of death among adults living with intellectual or developmental disabilities (IDD). However, few epidemiological studies exist worldwide quantifying inequalities in cancer stage at diagnosis and survival for people with IDD relative to those without IDD.
Methods: A population-based, retrospective cohort study was conducted using provincial health and social administrative data in Manitoba, Canada.
Background: Cancer is a leading cause of death among people living with intellectual or developmental disabilities (IDD). Although studies have documented lower cancer screening rates, there is limited epidemiological evidence quantifying potential diagnostic delays. This study explores the risk of metastatic cancer stage for people with IDD compared to those without IDD among breast (female), colorectal, and lung cancer patients in Canada.
View Article and Find Full Text PDFObjective: Oligodendrocyte progenitor cell differentiation is regulated by nutritional signals in the adult median eminence (ME), but the consequences on local myelination are unknown. The aim of this study was to characterize myelin plasticity in the ME of adult mice in health or in response to chronic nutritional challenge and determine its relevance to the regulation of energy balance.
Methods: We assessed new oligodendrocyte (OL) and myelin generation and stability in the ME of healthy adult male mice using bromodeoxyuridine labelling and genetic fate mapping tools.