Publications by authors named "R G Forsyth"
Article Synopsis
- The study aimed to analyze the impact of race, sex, comorbidities, and Medicaid status on health outcomes for patients with hard-to-heal venous leg ulcers (VLUs), comparing Medicare-only beneficiaries to Medicare/Medicaid dual-enrollees from October 2015 to October 2019.
- Using Medicare claims data, the research focused on treatment methods, demographic comparisons, and quantified outcomes like ulcer closure time and quality of life metrics, finding notable differences between the two groups.
- Results showed that dual-enrollees had a higher burden of comorbidities, greater representation from minority backgrounds, and significantly increased rates of emergency visits and cellulitis compared to Medicare-only enrollees, with early use of certain
Pediatric MOG-Ab-Associated Encephalitis: Supporting Early Recognition and Treatment.
Neurol Neuroimmunol Neuroinflamm
December 2024
Article Synopsis
- A study assessed children under 18 with antibodies to myelin oligodendrocyte glycoprotein (MOG-Ab), focusing on those with encephalitis who didn’t fit the criteria for acute disseminated encephalitis (ADEM), comparing them to those with ADEM.
- Out of 235 MOG-Ab positive patients, 33 had encephalitis and 74 had ADEM, with common symptoms including headache, seizures, and fever; 24% had a normal initial brain MRI.
- Findings indicated that children with encephalitis were generally older, more often admitted to intensive care, and had a delayed start of steroid treatment, suggesting MOG-Ab testing is essential for suspected encephalitis
Experiences of patients with hard-to-heal wounds: insights from a pilot survey.
J Wound Care
October 2024
Objective: To learn about the experiences of people who seek treatment for hard-to-heal wounds, we distributed a nationwide pilot survey, asking questions about the nature of their wound, how it shaped their daily lives, pathways to receiving care and experiences with treatment. The long-term objective is to quantify the journey of patients with hard-to-heal wounds to identify ideal intervention points that will lead to the best outcomes. This article summarises the findings, implications, limitations and suggestions for future research.
View Article and Find Full Text PDFBackground: The regenerative properties of stromal vascular fraction (SVF) in wound healing and scar formation are a subject of increasing clinical interest.
Objectives: Although preclinical studies have confirmed the angiogenetic, proliferative, and antifibrotic properties of SVF, there is limited clinical evidence from randomized controlled clinical trials.
Methods: Twelve patients who underwent abdominoplasty were included in this clinical study.
Article Synopsis
- Radiotherapy combined with immune checkpoint blockade (ICB) is being tested in a clinical trial involving oligometastatic cancer patients to see if it can enhance T-cell responses and improve outcomes.
- In this phase II trial, patients were split into two groups: one receiving a combination of treatments immediately after radiotherapy (arm A) and a control group receiving pembrolizumab alone (arm B).
- Results showed a higher one-year progression-free survival rate in arm A (10%) compared to arm B (0%), but overall, the study did not meet its main goal of improving long-term survival outcomes.