Publications by authors named "R G Feltbower"
Article Synopsis
- Adolescents and young adults (AYA) with cancer face unique challenges, particularly with central nervous system (CNS) tumors, which are the leading cause of cancer-related issues in this group.
- A study in England analyzed survival outcomes of 351 AYA patients receiving chemotherapy for high-grade malignant CNS tumors, revealing lower survival rates for non-White patients and those from lower socioeconomic backgrounds.
- The research highlights significant health disparities, showing that while 64.4% of White patients survived for three years, only 46.6% of non-White patients did, emphasizing the need for more investigation into these disparities to improve patient outcomes.
Objectives: To describe end of life care in settings where, in the UK, most children die; to explore commonalities and differences within and between settings; and to test whether there are distinct, alternative models of end of life care.
Methods: An online survey of UK neonatal units (NNUs), paediatric intensive care units (PICUs) and children/young people's cancer principal treatment centres (PTCs) collected data on aspects of service organisation, delivery and practice relevant to end of life outcomes or experiences (referred to as the core elements of end of life care) across three domains: care of the child, care of the parent and bereavement care.
Results: 91 units/centres returned a survey (37% response rate).
Background: High flow nasal cannula therapy (HFNC) and continuous positive airway pressure (CPAP) are two widely used modes of non-invasive respiratory support in paediatric critical care units. The FIRST-ABC randomised controlled trials (RCTs) evaluated the clinical and cost-effectiveness of HFNC compared with CPAP in two distinct critical care populations: acutely ill children ('step-up' RCT) and extubated children ('step-down' RCT). Clinical effectiveness findings (time to liberation from all forms of respiratory support) showed that HFNC was non-inferior to CPAP in the step-up RCT, but failed to meet non-inferiority criteria in the step-down RCT.
View Article and Find Full Text PDFBackground: There is emerging evidence on the impact of social and environmental determinants of health on paediatric intensive care unit (PICU) admissions and outcomes. We analysed UK paediatric intensive care data to explore disparities in the incidence of admission according to a child's ethnicity and the degree of deprivation and pollution in the child's residential area.
Methods: Data were extracted on children <16 years admitted to UK PICUs between 1st January 2008 and 31st December 2021 from the Paediatric Intensive Care Audit Network (PICANet) database.