Publications by authors named "R G Colantonio"

Transcatheter aortic valve implantation (TAVI) is the main treatment option for patients with severe aortic stenosis (AS) and older age. Improved imaging techniques have enabled better patient selection, and the main role is played by echocardiography. Methods more sensitive than LVEF in assessing cardiac function, such as global longitudinal strain (GLS) and myocardial work (MW), have become widespread, and other methods, like hemodynamic forces (HDFs), might be promising.

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  • PCI is an effective treatment for coronary artery disease, and this meta-analysis compares imaging-guided versus physiology-guided approaches specifically for managing intermediate coronary lesions.
  • The study reviewed seven relevant studies with 5701 patients, focusing on outcomes like major adverse cardiovascular events and target vessel revascularization over an average follow-up of 2.1 years.
  • Findings indicated that imaging-guided PCI led to lower rates of target vessel revascularization compared to physiology-guided PCI, although other outcome measures showed no significant differences, suggesting a potential preference for imaging guidance in clinical practice.
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  • The study compared transcatheter aortic valve replacement (TAVR) to surgical aortic valve replacement (SAVR) in low-risk patients, finding no significant differences in all-cause mortality, disabling stroke, or major cardiovascular events between the two procedures.
  • TAVR patients experienced more paravalvular leaks but had fewer cases of new-onset atrial fibrillation compared to those undergoing SAVR.
  • Overall, TAVR demonstrated similar long-term safety and effectiveness to SAVR, along with a greater effective orifice area but akin transvalvular mean gradients.
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  • The study reviews current literature on the outcomes of surgical aortic valve replacement (SAVR) versus transcatheter aortic valve replacement (TAVR) specifically for patients with bicuspid aortic stenosis (BAS), focusing on different valve morphologies in TAVR patients.
  • It analyzed eight studies comparing SAVR and TAVR outcomes, revealing no significant differences in death, stroke, or acute kidney injury rates between both methods, though TAVR had more permanent pacemaker implantations and SAVR had higher bleeding events.
  • The findings suggest that while TAVR is comparable to SAVR in short-term outcomes for BAS, it is associated with a higher rate of pacemaker use and lower rates of bleeding.
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Background: Chronic pre-procedural and acute post-procedural myocardial injury are frequently observed in patients with aortic stenosis undergoing transcatheter aortic valve implantation (TAVI). The aim of our study was to investigate the prognostic role of high sensitivity cardiac troponins (hs-cTns) elevation before and after TAVI.

Methods: 106 patients with severe aortic stenosis who underwent TAVI were enrolled.

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