[Method of separating and determining deacetylcephalosporin C in the fermentation media of Acremonium chrysogenum].

During fermentation of Acremonium chrysogenum, known cephalosporin-producing organism, there is formed, in addition, the main metabolite cephalosporin C. Its 3-desacetyl derivative, desacetylcephalosporin (DACS). The admixture of this derivative is not desirable.

[Antioxidant stabilization of the antifoaming agents used in the fermentation process].

Oils used as antifoaming agents in fermentation are subjected to oxidation to form various products, such as aldehydes, carboxylic acids, peroxides, etc. The negative effect of such products on biosynthesis of chlortetracycline by strains VUA 84 and Iz 22/VUPL of Str. aureofaciens was recorded.